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Molecular Genetics: Fill in the Blank

Fill in the Blank 20 questions Medicine & Health Sciences > Molecular Genetics by Katie Valentine
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Fill in the Blank (20)

Question 1
The structure of DNA is described as a double helix, resembling a twisted ladder.
Missing Word
helix
The double helix structure, proposed by Watson and Crick, describes the two-stranded, twisted shape of DNA.
Question 2
Each strand of DNA is composed of repeating monomer units called nucleotides, which consist of a sugar, a phosphate, and a nitrogenous base.
Missing Word
nucleotides
Nucleotides are the fundamental building blocks of DNA and RNA.
Question 3
In DNA, adenine always pairs with thymine, and guanine always pairs with cytosine, a principle known as complementary base pairing.
Missing Word
complementary
Complementary base pairing describes the specific hydrogen bonding interactions between DNA bases.
Question 4
DNA replication is considered semi-conservative because each new DNA molecule consists of one original strand and one newly synthesized strand.
Missing Word
semi-conservative
Semi-conservative replication ensures that each daughter DNA molecule retains half of the parental DNA.
Question 5
The enzyme DNA polymerase is primarily responsible for synthesizing new DNA strands by adding nucleotides to a growing chain.
Missing Word
polymerase
DNA polymerase is the key enzyme that catalyzes the synthesis of DNA during replication.
Question 6
On the lagging strand during DNA replication, DNA is synthesized in short segments known as Okazaki fragments.
Missing Word
Okazaki
Okazaki fragments are short, newly synthesized DNA fragments that are formed on the lagging template strand during DNA replication.
Question 7
Transcription is the process by which genetic information from a DNA template is used to synthesize a molecule of RNA.
Missing Word
Transcription
Transcription is the initial step in gene expression, converting DNA into RNA.
Question 8
In gene expression, RNA polymerase binds to a specific DNA sequence called the promoter to initiate transcription.
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promoter
The promoter is a DNA sequence that signals the start site for gene transcription.
Question 9
The type of RNA that carries the genetic code from DNA to the ribosome for protein synthesis is messenger RNA, or mRNA.
Missing Word
mRNA
mRNA molecules transport genetic information from the nucleus to the cytoplasm for translation.
Question 10
During translation, each three-nucleotide sequence on the mRNA, known as a codon, specifies a particular amino acid.
Missing Word
codon
A codon is a sequence of three nucleotides that forms a unit of genetic code in a DNA or RNA molecule.
Question 11
Transfer RNA, or tRNA, molecules carry specific amino acids to the ribosome, matching them to the appropriate mRNA codons.
Missing Word
tRNA
tRNA molecules are essential for translation, ensuring the correct amino acid is added to the polypeptide chain.
Question 12
The end product of translation is a polypeptide chain, which will fold into a functional protein.
Missing Word
polypeptide
A polypeptide is a linear chain of amino acids linked by peptide bonds, which forms a protein upon folding.
Question 13
In prokaryotes, a group of genes with related functions that are regulated together is called an operon.
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operon
An operon is a functional unit of DNA containing a cluster of genes under the control of a single promoter.
Question 14
A repressor protein binds to the operator region of an operon, blocking RNA polymerase and preventing gene transcription.
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repressor
A repressor is a regulatory protein that inhibits gene expression by binding to DNA and blocking transcription.
Question 15
Enhancer sequences are DNA regions that can be located far from a gene but still increase the rate of its transcription by binding to activator proteins.
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Enhancer
Enhancers are regulatory DNA sequences that boost the transcription of specific genes.
Question 16
An insertion or deletion of nucleotides that is not a multiple of three can cause a frameshift mutation, altering all downstream codons.
Missing Word
frameshift
A frameshift mutation changes the reading frame of the genetic code, leading to a completely different protein sequence.
Question 17
A silent mutation changes a single nucleotide but does not alter the amino acid sequence of the protein due to the redundancy of the genetic code.
Missing Word
silent
A silent mutation is a point mutation that has no observable effect on the phenotype.
Question 18
In Mendelian genetics, a dominant allele expresses its phenotype completely when present in either a homozygous or heterozygous state.
Missing Word
dominant
A dominant allele masks the expression of a recessive allele in a heterozygous individual.
Question 19
X-linked inheritance describes traits determined by genes located on the X chromosome, often showing different patterns in males and females.
Missing Word
X-linked
X-linked inheritance refers to the pattern of inheritance for genes on the X chromosome.
Question 20
When two different alleles are both fully expressed in the phenotype of a heterozygote, such as in blood type AB, the inheritance pattern is called codominance.
Missing Word
codominance
Codominance occurs when both alleles in a heterozygote are expressed equally and distinctly in the phenotype.

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